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Specs at a glance
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                              Max. measurement errorMass flow (liquid): ±0.5% 
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                              Measuring range0 to 75 kg/h (0 to 165,3 lb/min) 
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                              Medium temperature range3 to 60°C (37.4 to 140°F) 
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                              Max. process pressure6 bar (87 psi) 
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                              Wetted materialsMeasuring tubes: Stainless steel 1.4435, 316L 
 Hose connection nipple: Makrolon Rx 1805 polycarbonate
Field of application
Promass U 500 is the ideal single-use flowmeter for biopharmaceutical applications in the life sciences industry. It represents the response to the shift from multi-use to single-use devices and from batch to continuous manufacturing. Offering multivariable measurement, Promass U 500 provides enhanced reliability, high accuracy, and industry compliance according to cGMP. The flowmeter is especially suited for up- and downstream applications in the monoclonal antibodies (mAb) process.
The sensor comprises a disposable part, available in four line sizes, and a permanently installed base unit, fitting all line sizes. Heartbeat Technology automatically recognizes the flow range and verifies the validity of the factory calibration after installation. This simplifies commissioning and eliminates the need for calibration in the field. Equipped with built-in web server, WLAN, and up to 4 I/Os, the transmitter provides easy operation and additional process and device information.
Benefits
- Best-in-class measuring accuracy – Coriolis technology with multivariable measurement 
- Highest turndown ratio – one sensor fits all line sizes of disposable 
- cGMP compliance – designed according to the latest standards and guidelines, equipped with required attributes and documentation 
- Simple, fast commissioning – one-hand mounting and automated calibration data transfer 
- Self drainability or air bubble escape – thanks to different mounting angles 
- No field calibration needed – automated verification with integrated Heartbeat Technology 
- Digital integration – modern single pair Ethernet based communication protocols 
Videos
Xpert selection
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        Specialized products 
- Designed for demanding applications
Technical excellence
Simplicity
Variable
 
                              - 
        Standard products 
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
- 
        Specialized products 
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity | 
|---|---|---|
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 Fundamental selection Meet your basic measurement needs | Technical excellence | Simplicity | 
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 Lean selection Handle your core processes easily | Technical excellence | Simplicity | 
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 Extended selection Optimize your processes with innovative technologies | Technical excellence | Simplicity | 
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 Xpert selection Master your most challenging applications | Technical excellence | Simplicity Variable | 
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                                                            Technical Information (TI)
 TI Proline Promass U 500Coriolis flowmeter for single use EN 17/05/2024Language: English Version: 17/05/2024 File size: 5 MB File name: TI01783DEN_0124-00.pdf 
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                                                            Operating Instruction (BA)
 BA Proline Promass U 500Coriolis flowmeter 
 PROFINET over Ethernet-APL/SPEEN 04/04/202515/01/202517/05/2024Language: English Version: 04/04/2025 File size: 10.3 MB File name: BA02343DEN_0325-00.pdf 
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                                                            Operating Instruction (BA)
 BA Proline Promass U 500Coriolis flowmeter 
 Modbus RS485EN 15/01/202517/05/2024Language: English Version: 15/01/2025 File size: 9.7 MB File name: BA02342DEN_0225-00.pdf 
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                                                            Device Parameter (GP)
 GP Proline Promass 500Coriolis flowmeter 
 PROFINET over Ethernet-APLEN 17/05/202408/01/2024Language: English Version: 17/05/2024 File size: 3.3 MB File name: GP01173DEN_0224-00.pdf 
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                                                            Device Parameter (GP)
 GP Proline Promass 500Coriolis flowmeter 
 Modbus RS485EN 17/05/202401/08/202201/09/201901/12/201801/08/2018Language: English Version: 17/05/2024 File size: 3.8 MB File name: GP01062DEN_0724-00.pdf 
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                                                            Short Instruction (KA)
 KA Proline 500 – digitalTransmitter with Coriolis sensor 
 PROFINET over Ethernet-APLEN 15/01/202517/05/2024Language: English Version: 15/01/2025 File size: 1.8 MB File name: KA01710DEN_0225-00.pdf 
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                                                            Short Instruction (KA)
 KA Flowmeter Proline Promass UCoriolis sensor EN 15/01/202517/05/2024Language: English Version: 15/01/2025 File size: 1.2 MB File name: KA01686DEN_0225-00.pdf 
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                                                            Short Instruction (KA)
 KA Flowmeter Proline 500 – digitalModbus RS485 transmitter 
 with Coriolis sensorEN 15/01/202517/05/2024Language: English Version: 15/01/2025 File size: 1.6 MB File name: KA01709DEN_0225-00.pdf 
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                                                            Installation Instructions (EA)
 EA Replacing Small PartsProline 10, 400, 500, 500-digital, 800 Index B, 800 Index C, Cubemass EN 01/01/202415/12/202101/05/202101/04/202101/06/2020Language: English Version: 01/01/2024 File size: 1.2 MB File name: EA01024DA2_1223-00.pdf 
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                                                            Installation Instructions (EA)
 EA Replacing the Display ProtectionProline 400, 800 Index C, 500-digital EN 01/01/202415/12/202101/06/202002/08/201901/03/2018Language: English Version: 01/01/2024 File size: 480 KB File name: EA01093DA2_0723-00.pdf 
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